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Minhong Shen Selected Research

Micrococcal Nuclease

1/2022Pharmacological disruption of the MTDH-SND1 complex enhances tumor antigen presentation and synergizes with anti-PD-1 therapy in metastatic breast cancer.
1/2022Small-molecule inhibitors that disrupt the MTDH-SND1 complex suppress breast cancer progression and metastasis.
9/2014Structural insights into the tumor-promoting function of the MTDH-SND1 complex.

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Minhong Shen Research Topics

Disease

9Neoplasm Metastasis (Metastasis)
01/2022 - 09/2014
9Neoplasms (Cancer)
01/2022 - 01/2014
7Breast Neoplasms (Breast Cancer)
01/2022 - 09/2014
3Triple Negative Breast Neoplasms
01/2022 - 01/2019
3Adenomyosis
01/2019 - 02/2016
3Endometriosis
01/2018 - 07/2015
2Fibrosis (Cirrhosis)
04/2016 - 02/2016
1Lung Neoplasms (Lung Cancer)
01/2021
1Interstitial Nephritis (Tubulointerstitial Nephritis)
01/2019
1Metaplasia
04/2016
1Hemorrhage
07/2015
1Cysts
07/2015
1Carcinogenesis
01/2014
1Stomach Neoplasms (Stomach Cancer)
01/2014

Drug/Important Bio-Agent (IBA)

3Proteins (Proteins, Gene)FDA Link
01/2022 - 01/2019
3Micrococcal NucleaseIBA
01/2022 - 09/2014
3Transcription Factors (Transcription Factor)IBA
10/2020 - 09/2014
3Biomarkers (Surrogate Marker)IBA
04/2016 - 01/2014
2Immune Checkpoint InhibitorsIBA
01/2022 - 01/2022
2Prokaryotic Initiation Factor-3IBA
01/2019 - 01/2018
2Transforming Growth Factors (Transforming Growth Factor)IBA
04/2016 - 02/2016
1Messenger RNA (mRNA)IBA
01/2022
1Programmed Cell Death 1 ReceptorIBA
01/2022
1Neoplasm Antigens (Tumor Antigens)IBA
01/2022
1InterferonsIBA
01/2022
1Proteasome Endopeptidase Complex (Proteasome)IBA
10/2020
1Actins (F Actin)IBA
10/2020
1Deubiquitinating EnzymesIBA
10/2020
1UbiquitinIBA
10/2020
1Cadherins (E-Cadherin)IBA
11/2019
1ErbB Receptors (EGF Receptor)IBA
01/2019
1AntigensIBA
01/2019
1IntegrinsIBA
01/2019
1Focal Adhesion Protein-Tyrosine KinasesIBA
01/2019
1TamoxifenFDA LinkGeneric
02/2016
1CollagenIBA
07/2015
1BilirubinIBA
07/2015
1Ferritins (Ferritin)IBA
07/2015
1IronIBA
07/2015
1Tryptophan (L-Tryptophan)FDA Link
09/2014
1CarcinogensIBA
07/2014
1MicroRNAs (MicroRNA)IBA
01/2014

Therapy/Procedure

6Therapeutics
01/2022 - 02/2016
2Drug Therapy (Chemotherapy)
01/2022 - 12/2017
1Gastrectomy
01/2014